Titlebook: Cannabinoids; Roger G. Pertwee Book 2005 Springer-Verlag Berlin Heidelberg 2005 Cannabinoid.Nervous System.cannabinoid mechanisms of pain

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Effects of Cannabinoids on Hypothalamic and Reproductive Function,s and humans. Here we review the role of (endo) cannabinoids in the regulation of appetite and food intake. There is converging evidence that the hypothalamic endocannabinoid system changes after leptin treatment. Cannabinoid administration decreases heat production by altering hypothalamic neurotra

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Cannabinoids and the Digestive Tract,ved in the synthesis and metabolism of endocannabinoids. Immunohistochemical studies have shown the presence of CB. receptors on myenteric and submucosal nerve plexuses along the alimentary tract. Pharmacological studies have shown that activation of CB. receptors produces relaxation of the lower oe

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0171-2004 ed to THC activity. This had been pointed out by several highly regarded research groups that had shown that many of the effects seen with cannabinoids were related to those of biologically act978-3-540-26573-3Series ISSN 0171-2004 Series E-ISSN 1865-0325

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Springer Studium Mathematik - Bachelorof p42/p44 mitogen-activated protein kinase (MAPK), p38 MAPK and Jun N-terminal kinase (JNK) as signaling pathways to regulate nuclear transcription factors. The CB. receptor regulates K. and Ca. ion channels, probably via Go. Ion channel regulation serves as an important component of neurotransmiss

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Springer Studium Mathematik - Bachelor regulated during chronic agonist exposure, and gene expression is altered in disease states. There is a complex molecular architecture of the cannabinoid receptors that allows a single receptor to recognize multiple classes of compounds and produce an array of distinct downstream effects.

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Tabellierung und Interpolation,entally determined biological activities and the structural and electronic features of a series of small molecules. In a ligand-receptor approach, cannabinoid (CB) receptor models are probed for ligand binding sites and binding sites can be screened using energetic criteria, as well as ligand SAR an