Titlebook: Cancer Therapy; Differentiation, Imm Natale D’Alessandro,Enrico Mihich,Thomas R. Tritto Conference proceedings 1993 Springer-Verlag Berlin

Cognizance

Potential Role of Tumor Cell Antigen Modulation in Cancer Immunotherapy,cinoma cell population. Several clinical trials utilizing MAbs conjugated with radionuclides have shown preferential localization to human carcinomas (Colcher ., 1987a, b; Colcher ., 1990; Schlom ., 1989, 1991). Among the various MAbs generated, MAb B72.3 has been extensively used in clinical trials

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Natale D’Alessandro,Enrico Mihich,Thomas R. Tritto

变白

1010-8793 , which may support or evensubstitute chemotherapy: differentiation, immunomodulation,and inhibition of angiogenesis.Differentiation shouldnormalize neoplastic cells and makethem compatible with the host. Itsfeasibility withretinoids, interferons, chemotherapeutic and other agentsisdiscussed. Modula

ALTER

https://doi.org/10.1007/978-1-4020-6176-9osyl cytosine, daunomycin and actinomycin D have been shown capable of inducing tumor cell maturation [1,2,4,6,8,11,13,15,16,18–30], and we have examined the mechanism by which they initiate the maturation process.

等待

https://doi.org/10.1007/978-1-4020-6176-9ng that the increased number of malignant cells in the bone marrow and in the blood is due to an accumulation more than to a proliferative effect. The accumulation is the consequence of a long survival of malignant cells probably due to an impairment of the cell death program related to the immaturity of the cells.

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ATRA Therapy in Acute Promyelocytic Leukemia a Model for Differentiation Therapy,ng that the increased number of malignant cells in the bone marrow and in the blood is due to an accumulation more than to a proliferative effect. The accumulation is the consequence of a long survival of malignant cells probably due to an impairment of the cell death program related to the immaturity of the cells.