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Titlebook: Cancer Therapy; Differentiation, Imm Natale D’Alessandro,Enrico Mihich,Thomas R. Tritto Conference proceedings 1993 Springer-Verlag Berlin

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书目名称Cancer Therapy
副标题Differentiation, Imm
编辑Natale D’Alessandro,Enrico Mihich,Thomas R. Tritto
视频video
丛书名称Nato ASI Subseries H:
图书封面Titlebook: Cancer Therapy; Differentiation, Imm Natale D’Alessandro,Enrico Mihich,Thomas R. Tritto Conference proceedings 1993 Springer-Verlag Berlin
描述Provided here is a comprehensive examination of the basicand clinicalcondition of three innovative and promisingapproaches to cancer therapy, which may support or evensubstitute chemotherapy: differentiation, immunomodulation,and inhibition of angiogenesis.Differentiation shouldnormalize neoplastic cells and makethem compatible with the host. Itsfeasibility withretinoids, interferons, chemotherapeutic and other agentsisdiscussed. Modulation by biological agents, cytotoxiceffector cells and drugs is considered in attempts toboost endogenous antitumour defenses and/or to renderneoplastic cells more susceptible to the immune attack ofthe host. Finally, the important aspect of interfering withtumour blood vessel development and function is takeninto account.Consideringthe importance that chemotherapy has in cancertreatment and in view of a more and more integratedstrategy, the relationship between the aforementionedapproaches and chemotherapeutic agents and chemoresistanceis treated in detail.
出版日期Conference proceedings 1993
关键词Angiogenese; Immunodulation; Krebs; Onkologie; angiogenesis; cancer; chemoresistance; cheotherapy; immunomod
版次1
doihttps://doi.org/10.1007/978-3-642-84613-7
isbn_softcover978-3-642-84615-1
isbn_ebook978-3-642-84613-7Series ISSN 1010-8793
issn_series 1010-8793
copyrightSpringer-Verlag Berlin Heidelberg 1993
The information of publication is updating

书目名称Cancer Therapy影响因子(影响力)




书目名称Cancer Therapy影响因子(影响力)学科排名




书目名称Cancer Therapy网络公开度




书目名称Cancer Therapy网络公开度学科排名




书目名称Cancer Therapy被引频次




书目名称Cancer Therapy被引频次学科排名




书目名称Cancer Therapy年度引用




书目名称Cancer Therapy年度引用学科排名




书目名称Cancer Therapy读者反馈




书目名称Cancer Therapy读者反馈学科排名




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Yukio Kitade,Takashi Mori,Yukihiro Akaoerol (Habenicht et al.1980; Goldstein, Brown, 1990). Mevalonate is an essential precursor of several important cellular constituents, including: cholesterol, involved in cell membrane maintenance; heme A and ubiquinone, involved in electron transport; dolychol, required for glycoprotein synthesis; a
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Colon Cancer Cell Differentiation as Related to Methotrexate and 5-Fluorouracil Resistance,normal epithelial intestinal cells, i.e. enterocytes or goblet cells. Whether these cells, which behave like normal cells as to their differentiation characteristics and functions, possess particular adaptation properties which allow them to escape the cytotoxic effect of a number of stress conditio
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Interferon Regulation of Differentiation and Mechanisms,globin synthesis pathway. It is postulated that IFN induces the enhancing effect on differentiation via a marked increase of heme synthesis and number of transferrin receptors which in turn leads to an enhancement of globin chain synthesis.
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