Titlebook: Cancer Therapeutics; Experimental and Cli Beverly A. Teicher Book 1997 Springer Science+Business Media New York 1997 DNA.angiogenesis.cance

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Bis-Naphthalimidesicin and daunomycin, were originally isolated from natural sources, other compounds are synthetic organic molecules specifically designed as antineoplastic agents. Arcamone has classified these drugs on the basis of DNA interaction into:

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Cancer Drug Discovery and Developmenthttp://image.papertrans.cn/c/image/221212.jpg

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https://doi.org/10.1007/978-3-319-44165-8The use of mustard gas in World War I dramatically demonstrated the biological potential of alkylating agents. In addition to the vesicant action of sulfur mustard to the skin, conjunctiva, and respiratory tract, the myelosuppressive and lymphocytolytic effects were first documented by Krumbhaar and Krumbhaar in 1919 (.).

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