| 书目名称 | Cancer Stem Cell Resistance to Targeted Therapy |
| 编辑 | Cristina Maccalli,Matilde Todaro,Soldano Ferrone |
| 视频video | |
| 概述 | Presents ideas to focus future investigations that will assess the role of CSCs/CICs as prognostic and predictive biomarkers.Focuses on the clinical implications and challenges of targeting cancer ste |
| 丛书名称 | Resistance to Targeted Anti-Cancer Therapeutics |
| 图书封面 |  |
| 描述 | .This book represents an up-dated summary of the state of the art of the characterization of cancer stem cell/ cancer initiating cell (CSC/CIC) properties. An overview of the definition and biological properties of CSCs/CICs as well as the role of these cells in determining the resistance to standard and immune-based therapies is provided. It also discusses limitations in the achievement of a definitive biological characterization of CSCs/CICs due to their high extent of plasticity and heterogeneity that is also mutually driven by the interaction of these cells with the tumor microenvironment. The limitations in targeting CSCs/CICs with immunotherapy are also explained together with explorative combination approaches that could increase the susceptibility of these cells to the recognition by immune cells. ..This book is conceived for a broad audience, including students, teachers, scientific experts. The critical revision of available results in terms of immunological profile of CSCs/CICs and the efficacy in targeting these cells by immunological approaches, results in a comprehensive and up to date recapitulation of the field and provides interesting suggestions on how to focus f |
| 出版日期 | Book 2019 |
| 关键词 | Immunology; Molecular Medicine; Targeted Therapy; Cancer Stem Cell; Transcriptional Networks; Epigenetic |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-16624-3 |
| isbn_softcover | 978-3-030-16626-7 |
| isbn_ebook | 978-3-030-16624-3Series ISSN 2196-5501 Series E-ISSN 2196-551X |
| issn_series | 2196-5501 |
| copyright | Springer Nature Switzerland AG 2019 |
发表于 2025-3-21 18:52:17
