Titlebook: Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention; Wen G. Jiang,Robert E. Mansel Book 2000 Springer Science+B

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https://doi.org/10.1007/978-1-349-22738-9 ions and certain molecules. Although the structure has been known for decades, the molecular composition of the tight junction has only been recognised in the past decade. Molecules making up tight junctions include the transmembrane proteins occludin, claudin and paracellin, and cytoplasmic protei

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New Diplomacy In The Post-Cold-War Worldyhave micrometastatic disease at presentation. The lymphovascular function of the marrow represents an ideal location to detect micrometastasis. Various immunological methods have been used to detect micrometastases. Immunochemical staining using specific polyclonal or monoclonal antibodies singly o

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https://doi.org/10.1007/978-3-319-33873-6cause of mortality from the disease. The natural history of breast cancer remains controversial. It is unclear whether metastasis has already occurred by the time of presentation, especially in the caseof small, screen-detected tumours. The commonest sites of distant metastasis are bone, liver and l

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https://doi.org/10.1007/978-3-319-54226-3 immediate improvement in outcome is to ensure that patients receive optimum conventional management from site specialist multi-disciplinary teams working on Calman-Hine principles. Such treatment being tailored to patient needs with the use of relevant prognostic factors. Improved conventional trea

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https://doi.org/10.1007/978-3-030-60618-3s that normally encode for proteins which control the cell cycle, DNA repair and transcriptional events, the result is deregulation of cellular proliferation and other intracellular pathways, ultimately leading to tumour development.