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Titlebook: Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention; Wen G. Jiang,Robert E. Mansel Book 2000 Springer Science+B

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The Role of Integrin-Mediated Processes in the Biology of Metastasis, a better survival and invasive phenotype of the tumour cells themselves, or indirect, by promoting the growth of angiogenic blood vessels. In this review we provide an overview of integrin structure and function and discuss how integrin-dependent signals could affect the metastatic phenotype. We al
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The Role of Hyaluronan and Its Degradation Products in Tumour Angiogenesis and Metastasis,atic potential of these cell-lines i.e. tumour progression. The role of HYAL1 is more controversial, but the present study suggests that in some cell-lines this may also play a role in the progression of tumours to a metastatic/ angiogenic phenotype.
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The E-Cadherin/Catenin Complex in Invasion: The Role of Ectodomain Shedding,on described for many peptide receptors at the plasma membrane, and is mainly ascribed to the activity of two families of proteases: matrix metalloproteinases (MMPs) and adamilysins (ADAMs). Ectodomain shedding of E-cadherin seems to be instrumental in the functional downregulation of the E-cadherin
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New Dimensions of Information Warfare,on described for many peptide receptors at the plasma membrane, and is mainly ascribed to the activity of two families of proteases: matrix metalloproteinases (MMPs) and adamilysins (ADAMs). Ectodomain shedding of E-cadherin seems to be instrumental in the functional downregulation of the E-cadherin
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