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Titlebook: Calorie Restriction, Aging and Longevity; Arthur V. Everitt,Suresh I. S. Rattan,Rafael Cabo Book 2010 Springer Science+Business Media B.V.

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Food Restriction, Hormones, Genes and Agings show that when young male Wistar rats aged 60 days are hypophysectomized (HYP) and receive 1 mg cortisone once per week and the same amount of food as food restricted (FR) rats they age more slowly than control (C) or FR rats. HYP rats have the slowest aging in collagen fibre strength, kidney base
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, changes. Special emphasis is given to the first completed clinical studies which have investigated the effects of controlled, high-quality energy-restricted diets on both biomarkers of longevity and on risk factors for the development of chronic diseases of aging. Prolonged CR has been shown to ext
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on health and life-span effects of Calorie Restriction.Cove.Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over two to six years in heal
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