Titlebook: Calcium in Muscle Activation; A Comparative Approa Johann Caspar Rüegg Textbook 19861st edition Springer-Verlag Berlin Heidelberg 1986 Acti

conservative

Willibald A. Günthner (Ordinarius)um is the major determinant of contractile activity. What is the evidence? In 1966, Jöbsis and O’Connor made an important discovery. Toad muscle fibres loaded with the calcium indicator murexide turned faintly red upon electrical stimulation just before the fibre contracted, indicating the formation

Exhilarate

BILE

H. E. Mößmer,M. Schedlbauer,W. A. Günthnerof differences in the mode and rate of activation; however, adaptations in the contractile machinery itself could be equally important. In the following we shall be concerned with structures and mechanisms responsible for slowness or fastness.

dendrites

H. E. Mößmer,M. Schedlbauer,W. A. Günthner concentration, however, depends on the kind of regulatory proteins that sense and respond to intracellular concentrations of Ca.. These proteins are diverse. In vertebrate striated muscles, as we have seen in Chap. 4, the calcium sensor is troponin-C, located in the thin actin filaments. In such a

一起

H. E. Mößmer,M. Schedlbauer,W. A. Günthnere hemodynamic demands. In the beating heart, the contractile mechanism is switched on and off in a most regular manner by the rise and fall of the intracellular free calcium. To understand the control of the myocardium, therefore, we must first consider how the myoplasmic Ca. concentration is kept l

Eructation

H. E. Mößmer,M. Schedlbauer,W. A. Günthnertions. Smooth muscles may be spontaneously active, or they may contract in response to nervous or hormonal stimulation. For example, think of the constriction of blood vessels that may be influenced by sympathetic nerves releasing noradrenahne as a transmitter. Hormones and neurotransmitters exert t

Asymptomatic

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https://doi.org/10.1007/978-3-322-96325-3striated, and we may then agree with the statement of Prosser (1973): “No other tissue illustrates so well as muscle the theme of a common mechanism with variations adapted to specific functions.” Now, where do we stand?

单调女

Textbook 19861st edition, edited and transformed my innumerable notes and drafts into a readable manuscript; she also compiled the list of references and the Subject Index. I owe a great debt of gratitude to her and also to Claudia Zeugner, who prepared the figures with expertise and care. Then I would like to thank the De

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