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Titlebook: Breast Cancer: Biological and Clinical Progress; Proceedings of the C L. Dogliotti,A. Sapino,G. Bussolati Conference proceedings 1992 Sprin

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期刊全称Breast Cancer: Biological and Clinical Progress
期刊简称Proceedings of the C
影响因子2023L. Dogliotti,A. Sapino,G. Bussolati
视频video
学科分类Developments in Oncology
图书封面Titlebook: Breast Cancer: Biological and Clinical Progress; Proceedings of the C L. Dogliotti,A. Sapino,G. Bussolati Conference proceedings 1992 Sprin
影响因子The fight against breast cancer is expected to be effectively stimulated by interdisciplinary approaches and cross-fertilization between laboratory and clinical research findings. Of major importance are therefore meetings promoting fast transfer to clinical applications of findings by basic scientists. The present volume, reporting the proceedings of the 1991 Biennial Conference of the International Association for Breast Cancer Research, hopes to achieve this goal by presenting the most recent observations in the laboratory and their possible applications for diagnostic evaluations and clinical treatments. The sections of the book focus first on the oncogenes more likely involved in mammary tumorigenesis and on the polypeptide factors and steroid hormones affecting proliferation and possibly inducing carcinogenesis in breast epithelium. A section is devoted to the epidemiological studies and to the identification of risk factors, a way to select populations at higher risk and, possibly, to help in preventing the disease. Special emphasis is given to the establishment of diagnostic criteria and to the selection of prognostic factors, which must support an effective therapeutic pla
Pindex Conference proceedings 1992
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https://doi.org/10.1007/978-3-7091-5637-7disease. Recent studies have suggested the involvement of certain oncogenes and oncosuppressor genes in the development of this disease. Ras oncogenes in particular are activated in a high proportion of breast tumors and increased levels of ras protein correlates with poor prognosis. Ras signals may
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Michael S. Kilberg,Dieter Häussinger in many human cancers. The . gene was found to be overexpressed in squamous carcinomas (1 – 3), in renal cell carcinomas (4) and in glioblastomas (5 – 6); the . gene in carcinomas of the breast (7), ovary (8), stomach (9), colon (10) and salivary glands (10). In most cases . gene overexpression has
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Vittorio Sgaramella,Sandro Eridaniudies have now appeared describing the use of different transgenes and several different promotor systems to produce mammary tumors (.,.). The use of binary systems for tissue-specific promotion of oncogenes and the production of bigenic and trigenic animals through hybrid crosses promise to expand
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Eric D. Marsh,Amy R. Brooks-Kayale growth factors such as epidermal growth factor (EGF), transforming growth factor alpha (TGF-a), insulin-like growth factors (IGF-I and IGF-II), fibroblast growth factors (FGF) [1], and possibly platelet derived growth factor (PDGF) [2]. The other is the negative pathway involving agents such as me
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