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Titlebook: Brain Edema IX; Proceedings of the N Umeo Ito (Director and Neurosurgeon in Chief),Alex Conference proceedings 1994 Springer-Verlag/Wien 19

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An Assessment of Progression of Brain Edema with Amino Acid Levels in Cerebrospinal Fluid and Changecreased thereafter. Significant increases in spike discharge and disappearance of fast wave (p < 0.02), and increase in AAs were concurrently detected. The AAs originated from necrosis in the lesion. During the next 4 hours, increase of phenylalanine, tyrosine, and valine continued (p < 0.05). Slow
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Role of Serotonin and Prostaglandins in Brain Edema Induced by Heat Stress. An Experimental Study inth ketanserin (a selective serotonin. receptor antagonist) or indomethacin (an inhibitor of prostaglandin synthesis) markedly reduced edema formation after 4 h HS in young animals. These heat stressed animals had considerably less extravasation of protein tracers as compared to the untreated group.
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Evolution of Brain Edema ConceptsThe evolution of brain edema research is outlined from early experimental studies to the development of present concepts and interpretations, as well as the establishment of criteria for the two main types of edema, cytotoxic and vasogenic.
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