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Titlebook: Brain Edema IX; Proceedings of the N Umeo Ito (Director and Neurosurgeon in Chief),Alex Conference proceedings 1994 Springer-Verlag/Wien 19

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Valeria Panebianco,Jurgen J. Fütterercreased thereafter. Significant increases in spike discharge and disappearance of fast wave (p < 0.02), and increase in AAs were concurrently detected. The AAs originated from necrosis in the lesion. During the next 4 hours, increase of phenylalanine, tyrosine, and valine continued (p < 0.05). Slow
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Carlo Nicola De Cecco,Marco Rengoth ketanserin (a selective serotonin. receptor antagonist) or indomethacin (an inhibitor of prostaglandin synthesis) markedly reduced edema formation after 4 h HS in young animals. These heat stressed animals had considerably less extravasation of protein tracers as compared to the untreated group.
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Mechanisms of Glutamate Induced Swelling in Astroglial Cellsr hand, blockade of the Glu carrier, or of pertussis toxin sensitive G-proteins reduced the Glu induced swelling. Blockade of Ba. or TEA sensitive K+ channels completely blocked the Glu induced swelling as did also blockade with furosemide of the Na./ K./C1. co-transporter. Glu induced swelling occu
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Neuroprotective NMDA Antagonists: the Controversy over Their Potential for Adverse Effects on Cortic antagonists but they have given rise to concern over the safety in use of NMDA antagonists as neuroprotective agents. In contrast, vacuolation has not yet been demonstrated with agents acting at the glycine (L-687,414) or polyamine (eliprodil) modulatory sites of the NMDA receptor complex suggestin
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Mechanisms of Glial Swelling by Arachidonic Acid pathway by BW 755C did not prevent glial swelling from AA, whereas it was reduced by SOD, or almost completely abolished by the aminoster-oid U-74389F, an antagonist of lipid peroxidation. Replacement of Na+- and Cl- -ions in the suspension medium by choline chloride was also associated with comple
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Morphological Changes of Cultured Neuronal and Endothelial Cells by Human Albumin of albumin solution, and the cells became circular after 10 minutes. In the E4 group, similar morphological changes were observed, but no such changes were seen in the EC group..Immunostaining revealed the presence of albumin in the intracellular space in both the N and E4 groups, but not the EC gr
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Metabolic Alterations Accompany Ionic Disturbances and Cellular Swelling During a Hypoxic Insult to g, and (4) a decrease in the intracellular incorporation of .C-leucine, and (5) increased glucose utilization. All of the results were statistically significant (p >0.05) and exhibited a dose response relationship with the exception of intracellular incorporation of .Ca which did not become signific
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Leukocyte/Endothelial Interactions and Blood-Brain Barrier Permeability in Rats During Cerebral Supeerebral administration of LTB. and the maximal response of leukocyte rolling and sticking was observed. Whereas the blood-brain barrier was not opened by cerebral superfusion with 1.5 or 15.0 nM LTB., for i.v. Na+-fluorescein, barrier leakage was promptly induced by 30.0 nM. The present findings dem
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