Titlebook: Brain Aging and Therapeutic Interventions; Mahendra K. Thakur,Suresh I.S. Rattan Book 2012 Springer Science+Business Media Dordrecht 2012

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充气女

Base Excision DNA Repair: The House Keeping Guardian for Genomic Stability in the Brain, keep driving metabolic changes that would lead to more viable progenies for survival and propagation. Thus natural evolution uses two opposing forces to improve the genetic makeup of the species. With the advent of organisms turning aerobic, the advantage of gains in energy production also paved th

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Role of Brain-Derived Neurotrophic Factor as a Modulator of Synaptic Plasticity,ifferentiation, but also functions in activity-dependent plasticity processes such as long-term potentiation (LTP), long-term depression (LTD), learning and memory. BDNF is synthesized as a precursor protein (proBDNF) that is proteolytically cleaved to form the mature protein. BDNF mediates its effe

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hegemony

,Brain Aging: Influence of Early–Life Events on Late-Life Brain Disorders,ellectual abilities. AD usually appears late in adult life, but when the disease initiates and how long the disease processes take to develop are presently unknown. To address this issue, the “Latent Early–life Associated Regulation” (LEARn) model has been proposed. This model explains the etiology

轻浮女

The Importance of the Environment in Brain Aging: Be Happy, Live Longer!,his demands development of effective therapeutic/preventive interventions aimed to slow down the negative effects of aging and extend health-span. Here, we overview the mechanisms underlying brain aging in the context of the oxi-inflamm-aging theory, and discuss cutting edge promising findings openi

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Neurolipofuscin in Aging and Aluminum-Induced Aging: Possible Therapeutic Interventions,igment but it distorts the protein building machinery of the cell and interferes with the important autophagic process. Numerous forms of cellular stresses activate macroautophagy. Increased autophagic vacuoles (AVs) are associated with not only aging and ceroid disorders but also Alzheimer’s diseas

马具

Dietary Restriction as a Potential Intervention to Retard Age-associated Impairment of Brain Functi various environmental factors that are known to facilitate healthy aging process, dietary restriction (DR) seems to be the most promising regimen as it is known to prolong the lifespan, attenuate aging and prevent and/or delay the onset of numerous age associated diseases in model systems. In our r