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Titlebook: Boron Neutron Capture Therapy; Toward Clinical Tria Detlef Gabel,Ray Moss Book 1992 Springer Science+Business Media New York 1992 cancer.cl

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Borocaptate Sodium (BSH) Pharmacokinetics in Glioma Patients,tative conclusion 1) that BSH readily enters most malignant intracerebral tumors, 2) that some retention of the drug occurs in these tumor, leading to an improvement of the tumor-to-blood ratio over the first 18 hours, and possibly later, and 3) that BSH is virtually excluded from normal brain.
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Data Integration Technologies for Logistics,ion also included a review and bibliography of the Japanese results with BPA both in animals and in humans. Originally approved for studies in patients with melanoma, the BPA IND was amended to include patients with glioblastoma or breast cancer following the report that BPA selectively delivered boron to tumors other than melanoma..
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Udo Buscher,Rainer Lasch,Jörn Schönbergerand apply these studies to clinical use, it has been proposed to divide factors influencing “RBE” into two groups.; 1) estimated tolerance dose (ETD), which can be inferred from other experience reasonably well; and 2) compound factor (CF), which is much more variable as a function of microdosimetry and boron compound.
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https://doi.org/10.1007/978-3-030-85843-8trol tumor growth. Even the current aggressive multimodality therapy did not result in an average survival time of longer than 12 months. One is still faced with an infaust and very depressing prognosis for the patient suffering from a glioblastoma multiforme.
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A Phase 1 Biodistribution Study of p-Boronophenylalanine,ion also included a review and bibliography of the Japanese results with BPA both in animals and in humans. Originally approved for studies in patients with melanoma, the BPA IND was amended to include patients with glioblastoma or breast cancer following the report that BPA selectively delivered boron to tumors other than melanoma..
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Treatment Planning and Optimization for Pion Therapy,use of the particles, a new delivery technique was developed to fit the dose distributions in three dimensions to the target volume. With the developed therapy modality it was expected, after a stepwise optimization of the treatment, to reach an increased local control rate with equal or lower complication probability.
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