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Titlebook: Boron Neutron Capture Therapy; Toward Clinical Tria Detlef Gabel,Ray Moss Book 1992 Springer Science+Business Media New York 1992 cancer.cl

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发表于 2025-3-21 19:05:16 | 显示全部楼层 |阅读模式
期刊全称Boron Neutron Capture Therapy
期刊简称Toward Clinical Tria
影响因子2023Detlef Gabel,Ray Moss
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图书封面Titlebook: Boron Neutron Capture Therapy; Toward Clinical Tria Detlef Gabel,Ray Moss Book 1992 Springer Science+Business Media New York 1992 cancer.cl
影响因子The European Collaboration on Boron Neutron Capture Therapy (BNCT), conceived in 1987 and successful in 1989 in gaining financial support as a Concerted Action through the Medical and Health Research Programme of the Commission ofthe European Communities (CEC) in Brussels, considered it an opportune moment to hold its annual Plenary Meeting on 18-20 Septem­ ber 1991 as an International Workshop entitled "Towards Clinical Trials of Glioma with BNCT". The background to this consideration was influenced by the world-wide resurgence ofinterest in NCT over the last 2 decades and by the exemplifica­ tions at the Fourth International Symposium on Neutron Capture Therapy for Cancer held in Sydney in December 1990, where it was strongly indicated that within the next 2 years clinical trials would be started both in Europe and the United States. In particular at the High Flux Reactor of the Joint Research Centre of the CEC at Petten in The Netherlands, an epithermal neutron beam designed and installed in the summer of 1990 recently became operable at full reactor power. An extensive series ofexperiments, including the nuclear and radiobiological characterisation of the beam and a healthy tis
Pindex Book 1992
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Macroscopic and Microscopic Biodistribution of BSH in a Rat Glioma Model,n where they hide like “guerillas” among normal cells behind an intact blood-brain barrier (BBB). These cells give rise to the hitherto unavoidable recurrencies - even hemispherectomies fail to radically remove the tumour..
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a Concerted Action through the Medical and Health Research Programme of the Commission ofthe European Communities (CEC) in Brussels, considered it an opportune moment to hold its annual Plenary Meeting on 18-20 Septem­ ber 1991 as an International Workshop entitled "Towards Clinical Trials of Gliom
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Logistics, Supply Chains and Smart Factoriesresponse to the promise of several new boron localizing agents and the development of improved epithermal neutron beam delivery capabilities. Our plans for future activities encompass a number of specific areas for research emphasis.
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Sustainability and Industry 4.0 for the first time at full reactor power. The first measurements to characterise the neutron beam were made, followed shortly by some initial cell culture irradiation experiments, and the start of the . healthy tissue tolerance studies using the canine brain.
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Sandra Lechtenberg,Bernd Hellingrathtative conclusion 1) that BSH readily enters most malignant intracerebral tumors, 2) that some retention of the drug occurs in these tumor, leading to an improvement of the tumor-to-blood ratio over the first 18 hours, and possibly later, and 3) that BSH is virtually excluded from normal brain.
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Safety and Efficacy in Boron Neutron Capture Therapy,eatment, a boron compound that can selectively accumulate or be retained in the desired target cells. Subsequently, the organ containing the tumor is irradiated with neutrons. Boron-10, by virtue of its high neutron capture cross section, will give rise to two densely ionizing particles through the .B(n,α).Li neutron capture reaction.
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