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Titlebook: Blood Cells, Rheology, and Aging; Dieter Platt (Direktor) Conference proceedings 1988Latest edition Springer-Verlag Berlin Heidelberg 1988

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,Hemopoiesis as a Model for the “Biological Clock”,test capacity for replication in vitro, undergo 50±10 population doublings before division ceases in about 10–12 months. The events are divided into three phases. Phase I represents the primary culture, phase II the active replication period, and phase III the period when cell replication slows, cea
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Red Cell Membrane Lipids and Aging,ane. As shown in Table 1, the predominant lipids are phospholipids and unesterified cholesterol. The molar ratio of cholesterol to phospholipids is reported as ranging from 0.77 [2] to 0.90 [10]. The major classes of phospholipids represented are the choline-containing phosphatidylcholine and sphing
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The Effect of Host and Cell Age on the Rat Erythrocyte: Biochemical Aspects,ew]. In the course of these investigations many cellular and biochemical parameters were explored in an attempt to correlate decline in metabolic functions and structural changes and the increased propensity for sequestration of the erythrocyte by spleen and liver macrophages (Clark and Shohet 1985)
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The Effect of Host and Cell Age on the Rat and Human Erythrocyte: Cellular and Immunologic Aspects,apacity after the reticulocyte stage. As such, the erythrocyte has been studied as a model for cellular aging in young hosts. The erythrocyte provides an equally fascinating model for the study of the effects of host age on cellular aging.
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Mechanism for Elimination of Senescent Red Blood Cells from Circulation,red within the confines of the reticuloendothelial system (Ashwell and Morell 1974) and then removed from circulation by mononuclear phagocytic cells (Gemsa et al. 1972; Kay 1975). The aging process in human erythrocytes correlates well with increasing RBC density; hence, this parameter is often use
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