Titlebook: Biomedical Translational Research; Drug Design and Disc R.C. Sobti,Naranjan S. Dhalla Book 2022 The Editor(s) (if applicable) and The Autho

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Kimberley J Dripps,Martin Blumllly efficient pipeline to identify new indications for existing drugs. The candidates for repurposing are essentially marketed drugs or drugs that have been discontinued in clinical trials for reasons other than safety concerns. To date, repurposed drugs have been the consequence of serendipitous ob

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Landscape Analysis and Visualisationer cells, evolving from the “normal cells” of . are thus governed by the same rules. This is one of the reasons why, despite the advances in modern oncology, cure is not achievable in several cancers. Driven by the challenges posed by cancerous tissue, several new multipronged strategies have been e

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https://doi.org/10.5822/978-1-61091-751-3in elderly men. In drug repositioning studies conducted from our laboratory, we demonstrated that naftopidil has growth inhibitory effects by inducing G. cell cycle arrest in cancer cells, fibroblasts, and vascular endothelial cells. Moreover, naftopidil has been shown to bind directly to and inhibi

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