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Titlebook: Biomedical Translational Research; Drug Design and Disc R.C. Sobti,Naranjan S. Dhalla Book 2022 The Editor(s) (if applicable) and The Autho

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期刊全称Biomedical Translational Research
期刊简称Drug Design and Disc
影响因子2023R.C. Sobti,Naranjan S. Dhalla
视频videohttp://file.papertrans.cn/189/188111/188111.mp4
发行地址Presents genomic computational integrative approaches for drug re-positioning.Examines biomarker-based drug discovery with a reverse translational approach.Provides a brief overview of microdosing for
图书封面Titlebook: Biomedical Translational Research; Drug Design and Disc R.C. Sobti,Naranjan S. Dhalla Book 2022 The Editor(s) (if applicable) and The Autho
影响因子.This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. It emphasizes the importance of understanding biological and pathophysiological mechanisms underlying the disease to discover and develop new biological agents. The book uniquely explores the genomic computational integrative approach for drug repositioning. Further, it discusses the health benefits of nutraceuticals and their application in human diseases.  Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning. Finally, it summarizes the major challenges in drug development and the strategies for the rational design of the next generation more effective but less toxic therapeutic agents..
Pindex Book 2022
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Genomic Approaches for Drug Repositioningrch. Drug repositioning (DR) is an alternative approach to usurp already available drugs or drug candidates with FDA approval, which have been initially developed for specific diseases and re-establish their use for other diseases. Modern genomic methods for drug repositioning involve the usage of c
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Drug Repositioning of the Phenylpiperazine Derivative Naftopidil in Prostate Cancer Treatmentin elderly men. In drug repositioning studies conducted from our laboratory, we demonstrated that naftopidil has growth inhibitory effects by inducing G. cell cycle arrest in cancer cells, fibroblasts, and vascular endothelial cells. Moreover, naftopidil has been shown to bind directly to and inhibi
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Nanotechnology in Dentistryefined dental practice to be able to efficiently and effectively achieve the goal of positive oral health. The nanomaterials’ enhanced mechanical properties, increased durability in the oral environment, biocompatibility, better aesthetics and, above all, atraumatic experience to the patients make t
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