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Titlebook: Biology of the Lysosome; John B. Lloyd,Robert W. Mason Book 1996 Springer Science+Business Media New York 1996 biology.metabolism.nucleic

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Origin of Lysosomal Proteinsand transport pathway of newly synthesized soluble hydrolases to lysosomes are better understood than those involved in targeting of lysosomal membrane proteins. Soluble hydrolases are equipped with mannose 6-phosphate (M6P) residues that are recognized by specific receptors mediating their transpor
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Autophagydling of more than one class of macromolecule. This is illustrated in the perfused rat liver by the striking similarity in the accelerated responses of protein and RNA degradation during amino acid deprivation (see Table I).
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Lysosomal Metabolism of Proteinsricted to how they relate specifically to protein turnover. This chapter focuses on how the proteases function to hydrolyze proteins in the lysosome (for information on the pathological roles and the chemistry of the lysosomal proteases, see Lee and Marzella, 1994, and Mason and Wilcox, 1993).
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