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Titlebook: Biology of the Lysosome; John B. Lloyd,Robert W. Mason Book 1996 Springer Science+Business Media New York 1996 biology.metabolism.nucleic

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Kompetenz-Management für den Anlagenbaudegraded by acid hydrolases acquired by fusion with lysosomes. Although vacuoles of this type may be formed under pathologic conditions, autophagy is fundamentally a physiological process that plays indispensable roles in cell restructuring and in the ongoing turnover of cellular protein and other m
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Unternehmensführung & Controlling rate-limiting step in the lysosomal degradation of cytoplasmic proteins must be their initial sequestration. Indeed, the initial sequestration serves to remove cytoplasmic proteins from their functional site in the cell. Bulk sequestration of cytoplasm (macro-autophagy), described elsewhere in this
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https://doi.org/10.1007/978-3-663-08640-6rett and Kirschke, 1981). Detailed characteristics are known for several of the enzymes involved in lysosomal proteolysis, although recent data suggest that the current catalog of enzymes involved in protein degradation is by no means complete. Although the enzymes are the necessary tools for hydrol
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https://doi.org/10.1007/978-3-663-08640-6ycolipids, and glycoproteins. A portion of the cellular glycogen is also turned over in the lysosomes as a result of autophagy of cytoplasmic glycogen. The importance of the lysosomal catabolism of glycoconjugates for the normal functioning of cells and tissues is dramatically illustrated by the sev
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Strategisches Kompetenz-Management 65% of total rat liver cytoplasmic RNA is degraded per day, with 70–85% of this turnover occurring within the lysosomal compartment (Lardeux and Mortimore, 1987; Lardeux ., 1987, 1988; Heydrick ., 1991). Lysosomes contain an active repertoire of hydrolytic enzymes capable of completely degrading la
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Kristina Reiss,Aiso Heinze,Reinhard Pekruntions catalyzed by the lysosomal enzymes were hydrolytic permitted one to hypothesize that lysosomes could only play a part in the biotransformation of drugs and toxins. On the other hand, it was not difficult to imagine the necessity of such structures in protecting cells from exogenous material th
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