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Titlebook: Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation; Yuansheng Gao Book 20171st edition Springer Nature Singapore Pte Ltd.

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Cyclic GMP Signalinge (NO) and nitrovasodilators and by particulate guanylate cyclases (pGC) when stimulated with natriuretic peptides. The intracellular cGMP levels are determined by the balance of the synthesis of this cyclic nucleotide by sGC and pGC and its hydrolysis mainly by the type 5 phosphodiesterase. cGMP ex
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Kompendium der koronaren HerzkrankheitcAMP reflect its synthesis by adenylyl cyclase and its hydrolysis by phosphodiesterases, particularly the type 4 phosphodiesterase. The major mechanisms underlying cAMP-mediated vasodilatation include the activation of potassium channels, the activation of myosin light chain phosphatase, and the inhibition of RhoA/Rho kinase signaling.
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Metabolism of Vascular Smooth Muscleile activities. Many of these metabolites are actively involved in the regulation of vascular activities, such as nicotinamide adenine dinucleotide phosphate generated from the pentose phosphate pathway, and metabolites of .-arginine, heme, and cysteine. The current understandings of these subjects are discussed.
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Cyclic AMP SignalingcAMP reflect its synthesis by adenylyl cyclase and its hydrolysis by phosphodiesterases, particularly the type 4 phosphodiesterase. The major mechanisms underlying cAMP-mediated vasodilatation include the activation of potassium channels, the activation of myosin light chain phosphatase, and the inhibition of RhoA/Rho kinase signaling.
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