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Titlebook: Biology of Growth Factors; Molecular Biology, O Jeffrey E. Kudlow,David H. MacLennan,Avrum I. Gotl Book 1988 The Editor(s) (if applicable)

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Ina Grau,Ravena Penning,Hans-Jürgen Andreßubsequently for mouse embryo 3T3 cells.. At that time it was not clear whether there was more than one growth factor present in platelets. However, the major mitogen released by platelets, which is the subject of this report, has been termed the platelet-derived growth factor (PDGF).
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https://doi.org/10.33283/978-3-86298-627-9monstrated that the endosomal components are not lysosomes, . that a sequential transport of ligands and receptors among endosomal components can be observed, . and that morphologically different microdomains can be observed in continuous structures segregating ligands (vesicular) from receptors (tubular)..
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Regulation of Cell Growth and Transformation by the Epidermal Growth Factor Receptorptor is composed of three major structural elements. An extracellular EGF-binding domain composed of 621 amino acid residues, anchored to the plasma membrane by a single transmembrane region of 23 hydrophobic amino acids. The transmembrane region is followed by a sequence of mostly basic residues; a feature common to many membrane proteins.
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