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Titlebook: Biological Toxins and Bioterrorism; P. Gopalakrishnakone Living reference work 20200th edition

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楼主: 武士精神
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The Public Health Response to Potential Toxin Bioterrorism,l of awareness and low threshold of suspicion for toxin etiologies by medical practitioners, including those in hospital emergency departments and in private practice, is necessary to recognize a biological event involving a deliberate release of toxin has occurred. Where highly sensitive and specif
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Challenges in Developing Inhibitors Against Toxins,lly large surface area of the toxin-substrate interaction interface, the flexible loops lining the active site, involvement of a metal ion in the catalytic activity, and molten globule form of the enzyme at physiological temperature contribute to this challenge and are discussed.
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Counterfeit Botulinum Medical Products and Risk of Bioterrorism,ctable product. The potential for the sources of such products to become providers for bioterrorist activities is therefore of key importance. Can botulinum toxin from medical sources become a terrorist weapon? The background to this situation is discussed in detail, and the potential for such medic
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Evolutionary Traits of Toxins,ersity at every level, including species, individual organism, and even at the molecular level. Study of evolution in terms of molecular properties such as folding, flexibility, and dynamics provides us with another very unique and necessary dimension to examine molecular and submolecular mechanisms
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Cell-Based Assays for Neurotoxins,tions that are currently used, discusses advantages and limitations of differentiation methods, and reviews some initial applications. Finally, developing techniques are presented that are anticipated to increase throughput, sensitivity, and relevance. While the transition to moderate-throughput ass
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UICC International Union Against Cancerf trace levels of either toxin in biofluid samples is challenged by their short half-life in circulation due to efficient sequestering of these toxins into the target organs. This chapter provides an overview of the latest developments, from the authors’ laboratory as well as from open literature, i
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Natürliche Entwicklung des Krebsesepted diagnostic method for BoNTs is the mouse bioassay, which takes 4 days to complete. This clearly cannot meet the immediate need for clinical diagnosis of botulism, botulinum detection in field conditions, and screening of large scale samples. Consequently, the clinical diagnosis of botulism rel
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