Titlebook: Biological Toxins and Bioterrorism; P. Gopalakrishnakone Living reference work 20200th edition

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Aptamers as New Agents Against Biotoxins,t there are no effective countermeasures for most biological toxins. Aptamers are short single-stranded DNA or RNA oligonucleotides with high affinity and specificity to their targets. They are selected through the entire in vitro process and have many advantages over antibodies, leading them to hav

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Basic Chemistry of Botulinum Neurotoxins Relevant to Vaccines, Diagnostics, and Countermeasures,isk biothreat agents by the Centers for Disease Control and Prevention (CDC). They are the causative agents of botulism, a severe neuroparalytic disease which can be fatal in the absence of medical care. While the natural cases of botulism are rare, by virtue of their extreme toxicity, easy producti

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Challenges in Developing Inhibitors Against Toxins,ulinum neurotoxin, are potential agents of biological warfare and are also increasingly being used for therapeutic and cosmetic purposes. Despite the potential damage they could cause to human health, no drugs are currently available for post-intoxication therapy. Recent progress in drug discovery e

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Counterfeit Botulinum Medical Products and Risk of Bioterrorism, brought considerable benefits to patients, from children with cerebral palsy to older patients with stroke-related conditions. Aesthetic use alone is probably over 10 million treatments per year and rising rapidly. The latest licensed applications in pain treatment and urology are amongst a range o

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