Titlebook: Biological Reactive Intermediates; Formation, Toxicity, David J. Jollow,James J. Kocsis,Thomas Walle Book 1977 Springer Science+Business Me

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https://doi.org/10.1007/978-3-658-19515-1ion has been focused on the cytochrome P450-linked monooxygenase system which hydroxylates polycyclic aromatic hydrocarbons via highly reactive epoxide intermediates. These epoxide intermediates in turn undergo enzymatic reactions mediated by epoxide hydrase or glutathione-.-epoxide transferase, or

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instill

原谅

Discussionng metabolic inhibitors, but that CN is not a good inhibitor for this purpose. The oxidation of ethanol has not been proven to be mediated by a species of P450 which ethanol induces; however, this P450 does differ from the types of P450 inhibited by metyrapone and 7,8-benzoflavone (see text).

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