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Titlebook: Behavioral Neurobiology of Bipolar Disorder and its Treatment; Husseini K. Manji,Carlos A. Zarate Jr. Book 2011 Springer-Verlag Berlin Hei

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发表于 2025-3-21 19:39:25 | 显示全部楼层 |阅读模式
期刊全称Behavioral Neurobiology of Bipolar Disorder and its Treatment
影响因子2023Husseini K. Manji,Carlos A. Zarate Jr.
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发行地址Covers a wide range of methodologies including neuroimaging, genetics and epigenetics, animal models, translational research and psychopharmacology.Describes the most effective currently available tre
学科分类Current Topics in Behavioral Neurosciences
图书封面Titlebook: Behavioral Neurobiology of Bipolar Disorder and its Treatment;  Husseini K. Manji,Carlos A. Zarate Jr. Book 2011 Springer-Verlag Berlin Hei
影响因子This book offers the most up-to-date information about research surrounding the neurobiology of bipolar disorder as well as currently available and novel therapeutic options. The volume has assembled a widely respected group of preclinical and clinical researchers who bring their expertise to bear upon this illness by reviewing cutting-edge research and clinical evidence regarding the pathophysiology and treatment of bipolar disorder. Early chapters review the course and outcome and genetics of this highly heritable condition, including chapters on epigenetics and clinical endophenotypes. Several chapters offer a remarkably thorough and unique overview of the neurobiology of the disorder, including what is known from neuroimaging work and the development of animal models. Finally, the book covers treatment strategies for bipolar disorder, including both traditional and novel therapeutics, as well as non-pharmacological treatments. It offers both researchers and clinicians key insights into this devastating disorder.
Pindex Book 2011
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https://doi.org/10.37307/b.978-3-503-19992-1 chromatin structure. In this chapter, we revisit the epidemiological, clinical, and molecular findings in BPD and reanalyze them from the perspective of inherited and acquired epigenetic misregulation. Epigenetic research has great potential to enhance our understanding of the molecular basis of BPD.
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https://doi.org/10.1007/978-3-322-93436-9on to many neurodegenerative disorders. It would be reasonable to assume that neurons regulating mood are progressively impaired during the course of BPD. Further studies are needed to clarify which neural systems are impaired by mitochondrial dysfunction in BPD.
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The Role of the Aminergic Systems in the Pathophysiology of Bipolar Disorder,the permissive hypothesis. Evidence from select studies of cerebrospinal fluid, postmortem subjects, neuroimaging, genetic factors, and pharmacological agents will be used to reconcile these hypotheses. Possible explanations for discrepancies in these hypotheses are given, and directions for future studies are suggested.
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Bipolar Disorder: A Neurobiological Synthesis,al impairment, psychosocial disability, and diminished well-being. Furthermore, the disorder is frequently unrecognized, misdiagnosed, and mismanaged, and much still remains unknown about its pathophysiology.
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