Titlebook: Behavioral Neurobiology of Alcohol Addiction; Wolfgang H. Sommer,Rainer Spanagel Book 2013 The Editor(s) (if applicable) and The Author(s)

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Animal Models of Excessive Alcohol Consumption in Rodents,ting biological underpinnings and environmental factors that mediate/promote excessive levels of alcohol drinking. A major obstacle in this work has been the need to overcome the natural tendency of rodents to either avoid alcohol or consume it in limited amounts that typically do not produce overt

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Invertebrate Models of Alcoholism,ition towards alcoholism, several general requirements must be fulfilled. The animal should encounter ethanol in its natural habitat, so that the central nervous system of the organism will have evolved mechanisms for responding to ethanol exposure. How the brain adapts to ethanol exposure depends o

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The Dopamine System in Mediating Alcohol Effects in Humans,eurotransmitter systems and multiple psychological factors. In this context, the dopaminergic reinforcement system appears to be of fundamental importance. We focus on the excitatory and depressant effects of acute versus chronic alcohol intake and its impact on dopaminergic neurotransmission. Furth

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Stimulant and Sedative Effects of Alcohol,iterature on alcohol use and misuse. In this chapter we review studies that describe and attempt to measure various aspects of alcohol’s subjective, autonomic, motor, cognitive and behavioral effects from the perspective of stimulation and sedation. Although subjective sedative and stimulatory effec

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Translational Approaches to Medication Development, the last several decades has not resulted in a corresponding expansion of treatment options available to patients. In this chapter, we describe our experience with building translational research programs aimed at developing novel pharmacotherapies for alcoholism. The narrative is based on experien

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1866-3370 s and leaders in the field.With numerous illustrations.Inclu.The question how alcohol alters mood states and why this may end up becoming an addiction is puzzling alcohol researchers since decades. In this volume, an assembly of highly distinguished experts and leaders in alcohol addiction research