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Titlebook: Behavioral Neurobiology of Alcohol Addiction; Wolfgang H. Sommer,Rainer Spanagel Book 2013 The Editor(s) (if applicable) and The Author(s)

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发表于 2025-3-21 16:14:51 | 显示全部楼层 |阅读模式
期刊全称Behavioral Neurobiology of Alcohol Addiction
影响因子2023Wolfgang H. Sommer,Rainer Spanagel
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发行地址Covers the latest insights into alcohol addiction research and provides effective treatment solutions.Written by highly distinguished experts and leaders in the field.With numerous illustrations.Inclu
学科分类Current Topics in Behavioral Neurosciences
图书封面Titlebook: Behavioral Neurobiology of Alcohol Addiction;  Wolfgang H. Sommer,Rainer Spanagel Book 2013 The Editor(s) (if applicable) and The Author(s)
影响因子.The question how alcohol alters mood states and why this may end up becoming an addiction is puzzling alcohol researchers since decades. In this volume, an assembly of highly distinguished experts and leaders in alcohol addiction research provides lucid presentations of the current knowledge and research challenges as well as interesting viewpoints on future research directions aimed to stimulate communication and convergence between clinical and preclinical researchers, and to renew interest in the vibrant field of alcohol addiction research among a wide scientifically minded audience. .Five .Current Topics. are discussed in this volume: Neurobiological mechanisms of alcoholism, Genetics, Clinical phenotypes and their preclinical models, Brain imaging, and Translational approaches for treatment development, both pharmacological and non-pharmacological. These areas have in our opinion brought alcohol research substantially forward and influenced our thinking about how to reach our common paramount goal, namely to offer effective treatment solutions for an extensive group of patients with largely unmet medical needs..
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发表于 2025-3-21 22:13:28 | 显示全部楼层
Neurocircuitry Involved in the Development of Alcohol Addiction: The Dopamine System and its Accessand the possible involvement of acetaldehyde. Preclinical studies have provided the opportunity to dissect these interactions in some detail and although we do not fully comprehend the actions of ethanol there have been some great advances resulting in increased knowledge of the complexity of ethano
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What is in that Drink: The Biological Actions of Ethanol, Acetaldehyde, and Salsolinol, interaction of the ethanol molecule with several neurochemical systems within the CNS. While there are scientific findings that offer support for both of these stances, the reinforcing properties of alcohol are most likely generated through a complex series of peripheral and central effects of both
发表于 2025-3-22 08:07:53 | 显示全部楼层
Modeling the Diagnostic Criteria for Alcohol Dependence with Genetic Animal Models,els in an attempt to determine whether they support a single-factor or multiple-factor genetic structure. We conclude that there is modest support in the animal literature that alcohol tolerance and withdrawal reflect distinct genetic risk factors, in agreement with our human data. We suggest areas
发表于 2025-3-22 09:14:22 | 显示全部楼层
Non-Human Primate Models of Alcohol-Related Phenotypes: The Influence of Genetic and Environmental nvironmental factors (i.e., stress, individual’s sex, or alcohol exposure) interact to influence alcohol consumption. Studies in primates may also reveal selective factors have driven maintenance or fixation of alleles that increase risk for alcohol use disorders in modern humans.
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Modeling Alcohol Self-Administration in the Human Laboratory,ere subjects press a button to request multiple sequential alcohol exposures intravenously instead of drinking. This method has been demonstrated to be safe and provides increased experimental control of BAC and keeps subjects blind concerning the amount already self-administered. Peak exposures in
发表于 2025-3-22 22:56:41 | 显示全部楼层
Animal Models of Excessive Alcohol Consumption in Rodents,rmittent access to alcohol; (d) scheduled-induced polydipsia; and (e) dependence and withdrawal experience. Each of the models possesses unique experimental features that engender excessive levels of alcohol consumption. Both advantages and disadvantages for each model are described along with discu
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Invertebrate Models of Alcoholism,odels should offer advantages over traditional model systems and should offer new insights into alcoholism-related behaviors. In this review we will summarize behavioral similarities and identified genes and mechanisms underlying ethanol-induced behaviors in invertebrates. This review mainly focuses
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