| 期刊全称 | Base Excision Repair Pathway | | 期刊简称 | Methods and Protocol | | 影响因子2023 | Kishor K. Bhakat,Tapas K. Hazra | | 视频video | | | 发行地址 | Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts | | 学科分类 | Methods in Molecular Biology | | 图书封面 |  | | 影响因子 | This detailed volume provides a comprehensive set of experimental protocols and useful strategies to examine the repair of damaged bases via the Base Excision Repair (BER) pathway .in vitro. and in cells. Beginning with multiple molecular and cellular techniques to examine the excision of damaged bases from double-stranded DNA or DNA wrapped in a nucleosome, the book continues with sections covering procedures to detect and quantify the damaged bases, protein DNA crosslinks, and double-strand breaks, experimental procedures to identify DNA repair protein interactome by conventional tandem affinity purification followed by mass spectroscopy analysis, as well as the analysis of genome-wide binding of DNA repair proteins and copy number variations of the DNA damage response gene in tumors. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. .Authoritative and practical, .Base Excision Repair Pathway: Methods and Protocols. serves as a valuable r | | Pindex | Book 2023 |
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发表于 2025-3-21 17:20:49
