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Titlebook: Bacteriocins, Microcins and Lantibiotics; Richard James,Claude Lazdunski,Franc Pattus Conference proceedings 1992 Springer-Verlag Berlin H

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Introduction to the Microcin Sessioneened for the production substances that can pass through cellophane membranes with a molecular weight cutoff of about 10,000 daltons and inhibit the growth of lawns of standard laboratory strains of .. Using this as an operational definition, almost twenty different microcins have been identified t
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Uptake and Mode of Action of the Peptide Antibiotic Microcin B1787). The genes involved in the biosynthesis and secretion of this antibiotic as well as in the regulation of its production are described in an accompanying paper (Moreno ., 1991). MccB 17 is a glycine-rich peptide of about 3,200 daltons (Davagnino .., 1986). It inhibits semiconservative DNA replica
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Lactococcal Bacteriocins: Genetics and Mode of Actione inhibitory activity results from metabolic end products such as hydrogen peroxide, diacetyl, and organic acids (Lindgren & Dobrogosz, 1990). In addition, the bactericidal activity of many strains appeared to result from bacteriocin production (Klaenhammer, 1988). Although bacteriocins of lactic ac
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Biosynthesis of the Lantibiotic Pep5 and Mode of Action of Type A Lantibioticsdidehydroamino acids (dehydroalanine and dehydrobutyrine) and thioether amino acids (lanthionine and 3-methyllanthionine). Currently, two types of lantibiotics are distinguished: Type A which comprises elongated, screw-shaped, amphipathic peptides with molecular masses of more than 2100 Da (Pep5, su
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