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Titlebook: Antiviral Innate Immunity; Chunfu Zheng Book 2025 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Sci

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Lia Bijkerk,Wilma van der Heidegen infections, particularly RNA virus infections. In this chapter, we will introduce a “pull-down” method for identifying RIG-I-like receptors, related RNA helicases, Toll-like receptors, and other RNA sensors.
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https://doi.org/10.1007/978-90-313-7808-1 methods of protein lysine acetylation determination in virus-infected macrophages and embryonic fibroblast cells or proteins-overexpressed HEK 293 T cells in the context of antiviral innate immunity.
发表于 2025-3-23 22:36:13 | 显示全部楼层
A Guideline Strategy for Identifying Genes/Proteins Regulating Antiviral Innate Immunity,infectious diseases based on innate immunotherapy. In this section, we use the E3 ubiquitin ligase as an example to guide the identification of a protein belonging to the RING Finger (RNF) family that regulates the RIG-I-mediated IFN-I pathway through ubiquitination.
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CRISPR-Mediated Library Screening of Gene-Knockout Cell Lines for Investigating Antiviral Innate Imibit altered responses to infection. This integrated approach provides researchers in immunology and virology with a resource and a robust framework for uncovering the genetic basis of host-pathogen interactions and the arsenal of the innate immune system against viral invasions.
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CRISPR-Mediated Construction of Gene-Knockout Mice for Investigating Antiviral Innate Immunity,l, researchers can efficiently generate specific gene knockout mouse models, which not only helps in understanding the functions of the immune system but also offers a powerful experimental tool for exploring the mechanisms of antiviral innate immunity.
发表于 2025-3-24 14:23:54 | 显示全部楼层
Identifying RNA Sensors in Antiviral Innate Immunity,gen infections, particularly RNA virus infections. In this chapter, we will introduce a “pull-down” method for identifying RIG-I-like receptors, related RNA helicases, Toll-like receptors, and other RNA sensors.
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