Titlebook: Autoimmune Bullous Diseases; Text and Review Marcel F. Jonkman Book 20161st edition Springer International Publishing Switzerland 2016 Derm

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怒目而视

Drug-Induced Pemphigusthe drug to onset of the reaction is often relatively long compared to other cutaneous adverse drug reactions. Clinically, it can present as pemphigus foliaceus (most often), pemphigus erythematosus, pemphigus herpetiformis, or pemphigus vulgaris. Opposing to idiopathic pemphigus, pruritus, a prodro

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Structure of Hemidesmosomes and the Epidermal Basement Membrane Zoneng mechanical attachment, these adhesion units are extremely dynamic. They play a significant role in signaling pathways involved in the various important cell functions, such as differentiation, wound healing, and survival. Structurally, hemidesmosomes contain the following molecules: plectin (over

混合

Cutaneous Pemphigoidfferent structural proteins of hemidesmosomes in the epidermal basement membrane zone (EBMZ) (Table. 14.1). Cutaneous pemphigoid includes many subtypes, such as bullous pemphigoid (BP), nonbullous cutaneous pemphigoid (NBCP), Brunsting-Perry cicatricial pemphigoid, lichen planus pemphigoides (LPP),

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Mucous Membrane Pemphigoidoms and target antigens, such as ocular mucous membrane pemphigoid (OMMP), localized vulvar pemphigoid (LVP), and anti-laminin 332 MMP (anti-LN-332 MMP). Autoantibodies are directed against various structural proteins in the epidermal basement membrane zone (EBMZ), with the 180-kD antigen (BP180) as

易发怒

Epidermolysis Bullosa Acquisitaa. This subtype with scarring is named mechanobullous EBA, because blisters are evoked by sudden mechanical trauma, such as hitting the back of the hand to the edge of a table. The other subtype with erythematous lesions without scarring is named inflammatory EBA and may look like bullous pemphigoid

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IgA Pemphigusss against desmosomal and non-desmosomal proteins of the epidermis. Based on the clinics, histology, direct immunofluorescence, and autoantibody profile, it is classified in two types: the subcorneal pustulosis dermatosis (SPD)-type and the intraepidermal neutrophilic IgA dermatosis (IEN)-type. The first-line therapy is dapsone.

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Springer International Publishing Switzerland 2016

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,„Massaker am Ich“, Rausch, Turbulenz,ss against desmosomal and non-desmosomal proteins of the epidermis. Based on the clinics, histology, direct immunofluorescence, and autoantibody profile, it is classified in two types: the subcorneal pustulosis dermatosis (SPD)-type and the intraepidermal neutrophilic IgA dermatosis (IEN)-type. The first-line therapy is dapsone.