Titlebook: Autoimmune Bullous Diseases; Text and Review Marcel F. Jonkman Book 20161st edition Springer International Publishing Switzerland 2016 Derm

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书目名称Autoimmune Bullous Diseases影响因子(影响力)




书目名称Autoimmune Bullous Diseases影响因子(影响力)学科排名




书目名称Autoimmune Bullous Diseases网络公开度




书目名称Autoimmune Bullous Diseases网络公开度学科排名




书目名称Autoimmune Bullous Diseases被引频次




书目名称Autoimmune Bullous Diseases被引频次学科排名




书目名称Autoimmune Bullous Diseases年度引用




书目名称Autoimmune Bullous Diseases年度引用学科排名




书目名称Autoimmune Bullous Diseases读者反馈




书目名称Autoimmune Bullous Diseases读者反馈学科排名

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How to Take a Biopsyof invading inflammatory cells, and the presence, class, and distribution pattern of autoantibodies. For this, one needs to take a biopsy from a location with smallest change of sample error and specially fixate and the transport the specimen for the requested microscopic technique. All together, th

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Direct Immunofluorescence Microscopy is to detect in vivo antibodies in patient’s skin or mucosa. Direct immunofluorescence of pemphigus shows depositions of immunoglobulins and/or complement on the epithelial cell surface of keratinocytes, whereas pemphigoid shows linear deposition of immunoglobulins along the epidermal basement memb

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Immunoassays of individual patients. The three main immunoassays are immunoblotting, immunoprecipitation, and ELISA. All three make use of the ability of the autoimmune IgG to bind to the target antigen. Immunoblotting is used to visualize the apparent molecular mass of the antigen, thereby enabling its identif

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Structure of Desmosomes the tissue. Major proteins that compose desmosomes are desmogleins, desmocollins, plakoglobin, plakophilins, and desmoplakin. Isoforms of desmosomal proteins have different distribution in tissues, some of them being more ubiquitous and others being expressed only in specific tissues. The importanc

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Pemphigus Vulgarisor desmoglein 3 (Table .). Pemphigus can be divided into two major forms, pemphigus foliaceus (PF) and pemphigus vulgaris (PV). The mucosal dominant form of PV is characterised by blistering of the mucous membranes and antibodies directed against desmoglein 3. Patients with mucocutaneous PV have bli

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Pemphigus Foliaceusis. The common characteristic is the frequent presence of pathogenic anti-desmoglein 1 antibodies leading to bullae in the skin. Other characteristics – clinical, histological, pathogenesis, and therapy – vary and are specified in this chapter..Pemphigus foliaceus Cazenave first described by Cazenav

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