Titlebook: Apolipoprotein E and Alzheimer’s Disease; A. D. Roses,K. Weisgraber,Y. Christen Conference proceedings 1996 Springer-Verlag Berlin Heidelb

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https://doi.org/10.1007/978-1-4612-1264-5(Emerit and Chance 1992). The brain is believed to be particularly vulnerable to oxidative damage, as it contains high concentrations of easily peroxidizable lipids (i.e., those rich in polyunsaturated fatty acids), has regions particularly enriched in iron, and has comparatively low to moderate lev

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Graduate Texts in Contemporary Physicslinkage analysis has proven to be both powerful and successful in unraveling the genetic components of AD. Three loci have been identified; the amyloid precursor protein (APP) on chromosome 21, a newly identified gene on chromosome 14 and the apolipoprotein E locus (APOE) on chromosome 19. These loc

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Fundamental Concepts and Definitions,laments or from phosphorylation. To test this hypothesis, we are studying the interaction between apoE isoforms and tau using standard in vitro assays followed by western blotting and the relatively new technique of real-time bimolecular interaction analysis.

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