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Titlebook: Apolipoprotein E and Alzheimer’s Disease; A. D. Roses,K. Weisgraber,Y. Christen Conference proceedings 1996 Springer-Verlag Berlin Heidelb

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Interactions of Apolipoprotein E with Microtubule-Associated Proteins,laments or from phosphorylation. To test this hypothesis, we are studying the interaction between apoE isoforms and tau using standard in vitro assays followed by western blotting and the relatively new technique of real-time bimolecular interaction analysis.
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Graduate Texts in Contemporary Physicsage) families. The results of these analyses have shown three chromosomal regions that could potentially contain additional AD susceptibility loci. These regions of interest will be further evaluated using additional markers and AD families to confirm these initial findings.
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0945-6066 ith late-onset Alzheimer‘s disease, the common form of the disease defined as starting after sixty years of age. The role of apolipoprotein E in normal brain metabolism and in the pathogenesis of Alzheimer‘s disease are new and exciting avenues of research. This book, written by the most outstanding
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,Role of Apolipoprotein E in Alzheimer’s Disease: Clues from its Structure,n alleles of the plasma lipid-transporting protein, apolipoprotein (apo) E, was a major susceptibility gene (Strittmatter et al. 1993a; Corder et al. 1993; Saunders et al. 1993; Roses et al. 1995). It was also demonstrated that allelic variation at the apoE gene locus affects the progression of the
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