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Titlebook: Anticancer Drug Discovery and Development: Natural Products and New Molecular Models; Proceedings of the S Frederick A. Valeriote,Thomas H.

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https://doi.org/10.1007/978-3-662-38422-0 daily oral administration of “Nolvadex” (1,2). In view of this experience, it is reasonable to question whether there is either a clinical need, or pharmacological rationale, for novel antiestrogens. In our review of these questions, the answer was affirmative in both respects and led to the definition of a new drug target.
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Discovery of Natural Products from Microalgae and Marine Organisms,screening or a subsequence of synthesis of analogs of lead drugs (Table 1). Specifically, the discovery of cytotoxic agents from natural sources has had a rich and fruitful past with the identification of agents such as vincristine and taxol from plants and a number of antibiotics such as adriamycin from fermentations.
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The Therapeutic Potential of Novel Pure Antiestrogens, daily oral administration of “Nolvadex” (1,2). In view of this experience, it is reasonable to question whether there is either a clinical need, or pharmacological rationale, for novel antiestrogens. In our review of these questions, the answer was affirmative in both respects and led to the definition of a new drug target.
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Novel Strategies for the Discovery of Plant-Derived Anticancer Agents,0 species of flowering plants on this planet, of which it is estimated that 155,000 are found in the tropics (1), consequently, a rational strategy for drug discovery is required, since it is unrealistic to believe that all plants can be investigated biologically.
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Microorganisms: Strategic Sources of Novel Antitumor Agents,ound produced by a microorganism which kills or inhibits the growth of other microorganisms in low concentrations”. Now, the definition seems to extend to any bioactive compound produced by microorganisms.
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Prozessmodell des Rezeptionsmarktes,0 species of flowering plants on this planet, of which it is estimated that 155,000 are found in the tropics (1), consequently, a rational strategy for drug discovery is required, since it is unrealistic to believe that all plants can be investigated biologically.
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