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Titlebook: Anticancer Drug Discovery and Development: Natural Products and New Molecular Models; Proceedings of the S Frederick A. Valeriote,Thomas H.

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Interferons in Cancer Therapy: From Clinical Trials to New Potentials in Anticancer Drug Discovery iotechnological production, as well as experimental and clinical oncology. In the last few years, interferons have come of age and have found a respectable position among the most prominent new drugs.
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Andreas Maercker,Matthias SchützwohlMurine, human and chimeric monoclonal antibodies (MAbs) with specificity for human tumor antigens have achieved only limited success in the diagnosis and treatment of cancer (1–7). More promise is offered by the use of MAbs as carriers of drugs and toxins for tumor destruction and for delivery of radionuclides for tumor imaging and therapy (8–17).
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https://doi.org/10.1007/978-3-642-49709-4In the late 1960s, a crude alcohol extract from the bark of the Pacific Yew, ., was revealed to be cytotoxic . in the National Cancer Institute screening program (1,2). That extract’s principle, taxol, was isolated and characterized in 1971 by Wani et al (1).
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Selection and Manipulation of Immunoglobulins for Radionuclide Delivery,Murine, human and chimeric monoclonal antibodies (MAbs) with specificity for human tumor antigens have achieved only limited success in the diagnosis and treatment of cancer (1–7). More promise is offered by the use of MAbs as carriers of drugs and toxins for tumor destruction and for delivery of radionuclides for tumor imaging and therapy (8–17).
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