Titlebook: Antiangiogenic Agents in Cancer Therapy; Beverly A. Teicher,Lee M. Ellis Book 2008Latest edition Humana Press 2008 CNS.Chemokine.angiogene

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VEGF in the Adult in the adult in maintaining endothelial cell (EC) survival and fenestration, as well as its action on non-ECs. Properties that may affect VEGF action . are discussed. Finally, implications for use in anti- and pro-angiogenic therapy are proposed.

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,Die Erscheinungen an den Grenzflächen,ns, respectively, to supply and drain the tumor microvasculature. This classification has helped to elucidate the steps and mechanisms by which tumors induce new blood vessels and hopefully will lead to the identification of new therapeutic targets that can improve anti-angiogenic tumor therapy.

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Type-1-Diabetes

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The Role of Integrins in Tumor Angiogenesis Currently, humanized or chimeric antibody antagonists of integrins α5β1, αvβ3 and αvβ5 and peptide inhibitors of these integrins are in clinical trials as angiogenesis-inhibiting agents for cancer therapy.

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Chemokines in Angiogenesisin the regulation of angiogenesis. Based on their structure, CXC chemokines can be divided into two groups that either promote or inhibit angiogenesis, and they are therefore uniquely placed to regulate net angiogenesis in both physiological and pathological conditions including cancer growth.