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Titlebook: Antiangiogenic Agents in Cancer Therapy; Beverly A. Teicher,Lee M. Ellis Book 2008Latest edition Humana Press 2008 CNS.Chemokine.angiogene

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Einführung in die Physikalische Chemieival, treatment resistance, enhanced invasion, and metastasis. Results indicate that concurrent targeting of both tumor and endothelial cells may be of central importance in improving treatment responses to both radiation and chemotherapy.
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Einführung in die Physiologie des Menschen in the adult in maintaining endothelial cell (EC) survival and fenestration, as well as its action on non-ECs. Properties that may affect VEGF action . are discussed. Finally, implications for use in anti- and pro-angiogenic therapy are proposed.
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The Extracellular Matrix and VEGF Processingion on the question of how VEGF becomes released from the extracellular environment and contributes to tumor neovascularization. We discuss this point in the larger context of matrix interaction with growth factors and their modulation by matrix metalloproteinases (MMPs).
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Newer Vascular Targets-3 is an intracellular phosphatase that is expressed not only in tumor vasculature but in aggressive disease. SAGE analysis of subpopulations of tumors has provided useful leads for new vascular targets. It remains to the basic scientists to elucidate the function of these proteins and to the “drug
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