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Titlebook: Anti-Inflammatory Drugs; John R. Vane,Sergio H. Ferreira Book 1979 Springer-Verlag Berlin Heidelberg 1979 Antiphlogistikum.Drugs

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Screening and Assessment of the Potency of Anti-Inflammatory Drugs in vitroctory. . et al. (1973) stated bluntly: “All of these in vitro methods are virtually useless for a predictive assessment of drugs in vivo. They are useful only after drugs are discovered in other systems.” The above statement was justified when in vitro methods relied entirely on non-specific interac
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Experimental Models of Arthritis in Animals as Screening Tests for Drugs to Treat Arthritis in Man . alluded to “the temptation to select the present, inadequate drugs, design tests that give positive results and then with the aid of these tests to search for further compounds giving positive results. Such methodology may lead only to ‘old’ antiinflammatory agents instead of ‘new’.” More recentl
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