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Titlebook: Anti-Inflammatory Drugs; John R. Vane,Sergio H. Ferreira Book 1979 Springer-Verlag Berlin Heidelberg 1979 Antiphlogistikum.Drugs

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Evaluation of the Toxicity of Anti-Inflammatory Drugspeople in the United States suffering from arthritis (., 1975). About half of this population is under medical care and the other half is self-treated; of those under medical care, one-third require chronic drug administration, and the remainder, intermittent administration. Arthritis is a prevalent
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Mode of Action of Anti-Inflammatory Agents Which are Prostaglandin Synthetase Inhibitors human acute and chronic inflammation which have the common property of inhibiting fatty acid oxidative cyclization, in particular the formation of prostaglandins (PGs) and throm-boxanes. We have retained for this group of substances the term PG synthetase inhibitors because thromboxane synthetase c
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Cytostats with Effects in Chronic Inflammationinic have a tolerable therapeutic index. The acceptability of some of these toxic drugs may be due to any one or more of the following reasons: (1) they have a reversible effect on cell populations that turn over slowly; (2) they mainly delete cells from populations with a high rate of generation; (
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Oedema and Increased Vascular Permeabilitys by the membrane resistance of isolated cells; and anti-epileptic drugs by antagonism of electroshock-induced convulsions. Practically, it does not matter whether one measures a . in an assay rather than the . effect, so long as these vary together in a known manner.
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