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Titlebook: Annual Update in Intensive Care and Emergency Medicine 2015; Jean-Louis Vincent Book 2015 Springer International Publishing Switzerland 20

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Combatting Resistance in Intensive Care: The Multimodal Approach of the Spanish ICU “,” Program as a public health crisis [1]. Management of infections caused by these pathogens is often difficult due to the scarcity of available active drugs..The last report of the European Antimicrobial Resistance Surveillance System (EARSS) network, which includes 30 European countries, describes a general
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Immune System Dysfunction and Multidrug-resistant Bacteria in Critically Ill Patients: Inflammasonesidualized therapy for critically ill patients with sepsis. Clinicians tend to manage patients according to evidence-based guidelines that are derived from large randomized trials in which single patient characteristics and types of infection are rarely considered. But, as is well known, different ty
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Tachycardia in Septic Shock: Pathophysiological Implications and Pharmacological Treatmentctice the pathophysiological implications of an increase in heart rate are often undervalued. The importance of elevated heart rate and its role in determining or contributing to cardiovascular diseases began to be recognized at the end of the 1970s. Nowadays, it is clear that tachycardia represents
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Hyperoxia in Intensive Care and Emergency Medicine: Dr. Jekyll or Mr. Hyde? An Update vital for survival of mammalian cells since it allows for a sustained, high synthesis rate of adenosine triphosphate (ATP) in the respiratory chain because of its unique properties as a final electron acceptor [1]. On the other hand, this chemical property also renders it one of the strongest oxidi
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Extracorporeal Gas Exchange for Acute Respiratory Failure in Adult Patients: A Systematic Reviewssociated with tidal ventilation are known to aggravate lung injury in this setting [1]. Furthermore, profound gas-exchange abnormalities threatening patients’ lives can occur in the most severe forms of the disease despite recourse to conventional salvage therapies [2, 3]. Extracorporeal gas exchan
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Update on the Role of Extracorporeal CO2 Removal as an Adjunct to Mechanical Ventilation in ARDSuid balance, acute respiratory distress syndrome (ARDS) remains a devastating disease [1, 2]. Mortality rates for ARDS have decreased over time but still remain around 40%, in large part a result of the hemodynamic complications of this syndrome [3]. ARDS has various etiologies and early diagnosis a
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https://doi.org/10.1007/978-3-658-34542-6costs. Early identification of causative pathogens plays a critical role in the administration of appropriate antibiotic therapy and patient outcomes. In particular, in patients with clinical suspicion of VAP, respiratory samples should be obtained promptly to corroborate the provision of effective
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