Titlebook: Annual Update in Intensive Care and Emergency Medicine 2015; Jean-Louis Vincent Book 2015 Springer International Publishing Switzerland 20

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悬崖

Viral Sepsisproduction of interferons [2]. Interferons prevent the local spread of viruses, whereas antibodies prevent viremia, ensure long-term immunity and sensitize infected cells to be destroyed by T-cells and macrophages [3, 4]. Cell-mediated immunity leads to an increase in cytotoxic cells that then relea

Cirrhosis

Light and Shade of New Antibiotics a new standardized international terminology for describing acquired resistance profiles in bacteria that are often responsible for healthcare-associated infections and that are prone to multidrug resistance [3]. Multidrug resistance was defined as non-susceptibility to at least one agent in three

不断的变动

Combatting Resistance in Intensive Care: The Multimodal Approach of the Spanish ICU “,” Programminous emerging threat is the appearance of Gram-negative microorganisms harboring new beta-lactamases that confer high-level resistance to all available classes of beta-lactam antibiotics [6]. Concerning Gram-positive bacteria, methicillin-resistant . (MRSA) and . spp. resistant to vancomycin conti

角斗士

Immune System Dysfunction and Multidrug-resistant Bacteria in Critically Ill Patients: Inflammasonesrstanding the cause. Antibiotic therapy alone in these patients is frequently insufficient, so it is necessary to study an alternative way to make sure that the immune response can actively participate in the elimination of the pathogens [1]. Infection with MDR bacteria frequently occurs in debilita

调整

Tachycardia in Septic Shock: Pathophysiological Implications and Pharmacological Treatmentrate not only represents a clinical sign of altered cardiac function but also contributes to cardiac dysfunction. Although the role of an elevated heart rate is well established and has clearly been linked to outcome in cardiology patients, the topic has gained less attention in septic patients. To

extrovert

匍匐前进

β-Blockers in Critically Ill Patients: From Physiology to Clinical Evidencen increased incidence of hypotension, bradycardia and bleeding [8]. Over the years, these surprising results led to different changes in practice guidelines; specifically, the recent 2014 American College of Cardiology/American Heart Association (ACC/AHA) guidelines recommend that perioperative β-bl

小教堂

hematuria