Titlebook: Angiotensin-(1-7); A Comprehensive Revi Robson Augusto Souza Santos Book 2019 Springer Nature Switzerland AG 2019 Angiotensin.Angiotensin (

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https://doi.org/10.1007/978-3-658-00054-7 RAS is a dual function system in which the final effects are primarily driven by the balance between two opposite axes: the first formed by angiotensin converting enzyme (ACE), Angiotensin (Ang) II, and Ang type 1 receptor and the second comprising ACE2, Ang-(1-7), and Mas receptor. In this chapter

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ASSER International Sports Law Seriesases: pulmonary hypertension (PH), acute respiratory distress syndrome (ARDS), asthma, and pulmonary fibrosis. Understanding the involvement of renin angiotensin system (RAS) in pulmonary inflammation may open new therapeutic possibilities for the treatment of respiratory diseases. Studies to date s

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https://doi.org/10.1007/978-94-6265-048-0in system (RAS), with crucial metabolic relevance. While Ang II is increased in endocrine disorders such as obesity, diabetes, and dyslipidemia, important studies showed that augmented activation of angiotensin-converting enzyme 2 (ACE2)/Ang-(1-7)/Mas axis is able to revert hormonal dysregulation im

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Perspectives and Current Developments,muscle biology and disease. During exercise, Ang-(1-7) can modulate different organs helping to prevent and treat diseases such as chronic heart failure and diabetes. In skeletal muscle diseases, it has been found that Ang-(1-7) plays a protective role, counteracting the deleterious effects of angio

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Massimiliano Agovino,Gaetano Musellaction and expression of many cytokines and adhesion molecules and decreases leukocyte movement in vitro and in vivo. In animal models of inflammation, administration of Ang-(1-7) or its analogues is, in general, associated with inhibition of leukocyte influx and inflammatory tissue damage. In additi

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SpringerBriefs in Environmental Sciencestem (RAS). Due to its pleiotropic aspect and consequent beneficial effects in the body, this peptide is a target for developing new medications aimed to treat cardiovascular, renal, and metabolic diseases. The use of Ang-(1-7) by itself as a drug has been hampered by the naive concept that since it