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Titlebook: Angiotensin-(1-7); A Comprehensive Revi Robson Augusto Souza Santos Book 2019 Springer Nature Switzerland AG 2019 Angiotensin.Angiotensin (

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Robson Augusto Souza SantosThe first book addressing in full the most important aspects of Angiotensin-(1-7).An integrative view of the modulatory biological actions of Ang-(1-7) within the renin-angiotensin system.Discusses th
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Tools for Studying Angiotensin-(1-7)There are many genetic and pharmacological tools available for the study of the pharmacological and pathophysiological implications of angiotensin-(-1-7). In this chapter, we address the pharmacological tools for interfering with the formation and actions of this heptapeptide.
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The Angiotensin-(1-7) Axis: Formation and Metabolism Pathways, that opposes many actions of the Ang II-AT.R axis. In lieu of the complexity of this system, the chapter discusses the current evidence on the enzymatic cascade of the Ang-(1-7) axis of the RAS regarding the peptidases that contribute to the formation and degradation of the peptide in the circulati
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Heart – Coronary Vessels and Cardiomyocytes is an endogenous counter-regulatory pathway within the RAS whose actions are opposite to the vasoconstrictor/proliferative axis of the RAS formed by ACE/Ang II/AT. receptor. In this chapter, we will briefly discuss the main findings concerning the biological role of Ang-(1-7) and its receptor Mas f
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Kidneybtotal nephrectomy, diabetes nephropathy, adriamycin induced-nephropathy, and acute renal injury. The renoprotection of ACE2/Ang-(1-7)/Mas axis is mainly attributed to reduction of oxidative stress, inflammation, and fibrosis. Few human studies support a compensatory activation of the counter-regula
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Liverth. In this context, to better comprehend the role of RAS components in liver failure might pave the way for the search of potential predictive biomarkers as well as the development of novel therapeutic approaches. Valuable data have been generated from preclinical and clinical studies. Herein, we s
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Concluding Remarksonship expected from evaluations using conventional pharmacokinetics models. Actually, as illustrated in different chapters, there are many publications showing that a single daily oral administration of the inclusion compound Ang-(1-7)/HPB-cyclodextrin is capable of producing beneficial effects in
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n extensive publication record in the field, including the publication of the book .The Protective Arm of the Renin Angiotensin System .(Academic Press, 2015)..Angiotensin-(1-7) will make a unique contribution 978-3-030-22698-5978-3-030-22696-1
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