Titlebook: Angiogenesis; From the Molecular t Michael E. Maragoudakis Book 2000 The Editor(s) (if applicable) and The Author(s), under exclusive licen

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Nicola Berry,Yasutomi Nishizukaing and ischemia. We have recently examined .and .the ability of two potent angiogenic compounds, SIKVAV (a peptide derived from the alpha chain of laminin-1) and Neuropeptide Y (NPY) to revascularize ischemic tissue. These compounds were tested in an ex vivo capillary sprouting angiogenesis assay t

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Jacques Joyard,Maryse A. Block,Roland Doucey endothelial cells and megakaryocytes in culture. In previous studies we have shown that protein S acts as a mitogen for cultured human vascular smooth muscle cells. The synthesis and secretion of protein S by endothelial cells suggests that in addition to its role in the coagulation cascade, prote

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From anemia to cerebellar dysfunction,therapeutic strategy against cancer (Folkman, 1992). The formation of new blood vessels permits rapid expansion of the tumor and increases the risk of metastatic spread. The process of angiogenesis involves three distinct steps as outlined in Figure 1. Angiogenesis is initiated by the secretion of c

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Facilitative glucose transporters, development and pathological conditions such as cardiovascular diseases and cancer metastasis. Type IV collagenases (gelatinase A/MMP-2 and gelatinase B/MMP-9) may be critical in the early steps of angiogenesis, the digestion of basement membrane and the migration of endothelial cells from the exis

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Book 2000eece. .Angiogenesis, as a vastly complex biological process, has challengedresearchers from all basic scientific disciplines, includingpharmacology, biochemistry, physiology, embryology and anatomy. Thesignificance of this phenomenon for the study of disease states hasalso interested clinicians from

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