Titlebook: Algorithms in Bioinformatics; 15th International W Mihai Pop,Hélène Touzet Conference proceedings 2015 Springer-Verlag Berlin Heidelberg 20

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0302-9743 matics, WABI 2015, held in Atlanta, GA, USA, in September 2015. The 23 full papers presented were carefully reviewed and selected from 56 submissions. The selected papers cover a wide range of topics from networks to phylogenetic studies, sequence and genome analysis, comparative genomics, and RNA s

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BicNET: Efficient Biclustering of Biological Networks to Unravel Non-Trivial Modules,nding the cell behavior, dense biclusters can only identify modules where genes, proteins or metabolites are strongly connected. These modules are thus often associated with trivial, already known interactions or background processes not necessarily related with the studied conditions. Furthermore,

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Simultaneous Optimization of both Node and Edge Conservation in Network Alignment via WAVE,ion (NCF) to compare nodes across networks and an alignment strategy (AS) to find high-scoring alignments with respect to total NCF over all aligned nodes (or node conservation). Then, they evaluate alignments via a measure that is different than node conservation used to guide alignment constructio

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The Topological Profile of a Model of Protein Network Evolution Can Direct Model Improvement,enerate networks sharing topological characteristics with their empirical counterparts. It remains a challenge to assess, modify, and improve a model based on the topological values it generates. A large range of parameter values may produce a similar topology, and topological properties may vacilla

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Orthology Relation and Gene Tree Correction: Complexity Results,her hand, many tree-free methods, mainly based on sequence similarity, are also available. The link between orthology relations and gene trees has been formally considered recently from the angle of reconstructing phylogenies from orthology relations. Here, we rather consider this link from a correc

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Epithelium

A Sub-quadratic Time and Space Complexity Solution for the Dated Tree Reconciliation Problem for Setotic complexity associated with inferring coevolutionary interrelationships that exist between organismal trees. The leveraging of tree topology for coevolutionary analysis has been shown to be highly successful, with one recent result demonstrating a logarithmic space complexity reduction for the

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啤酒

Multiple-Ancestor Localization for Recently Admixed Individuals,netics. The treatment of ancestry as a continuum instead of a categorical trait has been recently advocated in the literature. Particularly, it was shown that a European individual’s geographic coordinates of origin can be determined up to a few hundred kilometers of error using spatial ancestry inf