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Titlebook: Advances in the Immunopathogenesis of Multiple Sclerosis; D. Gambi,P. A. Muraro,U. Ecari Conference proceedings 1999 Springer-Verlag Itali

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楼主: 瘦削
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Bruno Cartaxo,Gustavo Pinto,Sergio Soaresro [11, 12], is a powerful vasopermeabilizing molecule in vivo [13, 14], and promotes leukocyte adhesion and transmigration [15–17]. High PAF concentrations are toxic for endothelial cells, causing vacuolization and marked formation of blebs [12, 18].
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Can There Be Religion Without Gender?sceptible species by means of active immunization with CNS proteins and by passive transfer of encephalitogenic T cells to syngeneic recipients. Encephalitogenic T cells recognize myelin antigens and can be retrieved from the blood of both immunized and naive animals [4].
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From specificity to degeneracy to molecular mimicry: antigen recognition of human autoreactive and gents. After activation and upregulation of adhesion molecules, these cells can cross the blood-brain barrier; after reactivation by myelin antigens either directly or via the recruitment of other cells, the activated T cells damage the myelin sheath and oligodendrocytes.
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Neuronal control of the immunological microenvironment in the CNS: implications on neuronal cell deor the involvement of neurons in the regulation of MHC expression emerged from several studies using neuronal transection models. These models permit the analysis of cellular responses occurring locally, as well as those distant from the primary lesion, without interfering with the blood-brain barrier.
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Levels of platelet-activating factor in cerebrospinal fluid and plasma of patients with relapsing-rro [11, 12], is a powerful vasopermeabilizing molecule in vivo [13, 14], and promotes leukocyte adhesion and transmigration [15–17]. High PAF concentrations are toxic for endothelial cells, causing vacuolization and marked formation of blebs [12, 18].
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Experimental autoimmune encephalomyelitis in the common marmoset ,,sceptible species by means of active immunization with CNS proteins and by passive transfer of encephalitogenic T cells to syngeneic recipients. Encephalitogenic T cells recognize myelin antigens and can be retrieved from the blood of both immunized and naive animals [4].
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