Titlebook: War in the Body; The Evolutionary Arm W David Wick,Otto O Yang Book 2013 Springer Science+Business Media New York 2013 Drug Resistance.HIV/

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The Escape Formulacs, we must distinguish two contributions to viral fitness: one relating to the ability of HIV to grow in its target cells, independent of any immune response, and another reflecting immune pressure. Both appear in a heuristic formula for the rate of escape from CTL control, which we describe in this chapter.

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The CTL Model lymph nodes and other tissues, where they patrol for cells infected by pathogens. Each T-cell recognizes a specific antigen, which in our context is an “epitope”, a short segment of an HIV protein in a complex with an HLA molecule, exposed on the surface of an infected cell. T-cells that have not e

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