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Titlebook: 3D Sponge-Matrix Histoculture; Methods and Protocol Robert M. Hoffman Book 2018 Springer Science+Business Media, LLC, part of Springer Natu

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https://doi.org/10.1007/978-3-322-83506-2r ones, have been histocultured on Gelfoam. and tested for drug response. Quantitative and qualitative results show increasing cell kill with rising cytotoxic drug concentration, differential drug sensitivities of multiple cell types within individual cultured tumors, differential sensitivities to a
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https://doi.org/10.1007/978-3-322-83517-8tal cancer patients. In one study, 29 patients were treated with drugs shown to be ineffective in the HDRA, and all 29 cases showed clinical chemoresistance. In nine patients treated with drugs shown to be effective in the HDRA, six showed clinical chemoresponse and three showed arrest of disease pr
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https://doi.org/10.1007/978-3-322-83634-2e as well as prostate cancer. Gelfoam histoculture was used to measure androgen-independent and androgen-dependent growth of benign and malignant prostate tissue. The androgen-sensitivity index was significantly higher in 23 paired specimens of prostate cancer compared to benign prostate hypertrophy
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